Background: Prevention of colorectal carcinomas is based on early detection and removal of precancerous lesions. Our goal was to perform a comparison between clinicopathological features of adenomas/polyps developed in the presence and in the absence of a colon carcinoma. Materials and methods: We studied a total of 117 colon adenomas and polyps selected from the material of the Pathology Department of the Emergency County Hospital of Tîrgu Mureș. We compared and correlated through statistic analysis the clinicopathological factors, gender, age of the patients, localization, histological type, grade of dysplasia.
Results: 24.6% of A/P develop synchronously with a carcinoma and affect especially women and patients between 50–60 and 70–80 years; these are mainly tubular adenomas, localized more frequently in the left colon. Adenomas and polyps developed without a carcinoma are more frequent in males, in patients between 60–70 years, and are mainly tubulovillous adenomas.
Conclusions: One out of 4 colon carcinomas are associated with one or more precancerous lesions.