Tag Archives: mosaicplasty

Results of Osteochondral Mosaic Grafting in a Sheep Model

Szántó A1, Gergely I2, Pop TS2, Russu O2, Zuh S2 Zazgyva Ancuţa2, Nagy Ö2

1 County Emergency Hospital, Miercurea Ciuc, Romania
2 University of Medicine and Pharmacy, Department of Orthopaedics and Traumatolog, Tîrgu Mureș, Romania

Objective: We present the results of an experimental study in sheep on using autogenous, cylindrical osteochondral grafts for treating cartilage defects in the knee. The aim was to produce hyaline or hyaline-like cartilage on weight-bearing surfaces through autogenous osteochondral transplantation using special instrumentation and the mosaicplasty technique.
Methods: We used a sheep model – cartilage defects were made in the knees of 16 young sheep from the Tigaia breed. At 4 and 8 weeks postoperatively macroscopic, radiologic and microscopic examinations were performed on the transplanted sites and the donor sites.
Results: We found that grafts incorporated well in the recipient sites, showing good survivorship. Joint congruency was maintained, with 75 to 80% hyaline cartilage at the transplanted site.
Conclusions: Our results lead us to conclude that mosaic-like osteochondral grafting is an excellent treatment method for repairing chondral defects in major joints.

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Transchondral Drilling and Osteochondral Autografting (Mosaicplasty) in Knee Articular Cartilage Defects

Ivănescu A1, Melinte R2, Sólyom Á2, Moraru L3, Petrișor M4, Brânzaniuc Klara1

1 University of Medicine and Pharmacy of Tîrgu Mureș, Department of Anatomy and Embriology
2 County Emergency Clinical Hospital Tîrgu Mureș, Orthopedic Clinic II
3 County Emergency Clinical Hospital Tîrgu Mureș, Clinic of Cardiovascular Surgery
4 University of Medicine and Pharmacy of Tîrgu Mureș, Department of Medical Informatics and Biostatistics

Background: The cartilage is a complex and specialized tissue. It is extremely difficult to repair or to replace it, once damaged. The management of cartilage defects remains controversial and over the last five decades various treatment options and surgical techniques have been tried to optimize the clinical outcome.
Objective: The aim of this study is to evaluate, but not to compare the results of two of the most used cartilage repair techniques: trans-chondral drilling and osteochondral autografting.
Material and methods: Between January 2009 and June 2010, we performed 55 transchondral drillings and 10 mosaicplasties on patients with articular cartilage defects of the knee. All patients were followed up at 6 months. Hughston clinical and radiological scales were used to evaluate the patients in the transchondral drilling group.
Results: The Hughston Clinic score was 2 in 2 cases (3.6%), 3 in 5 cases (9.9%) and 4 in 48 cases (86.5%), giving over 95% of good results. The Hughston radiological score was 2 in one case (2%), 3 in 4 cases (7.3%) and 4 in 50 cases (90.7%). In the mosaicplasty group,the average area of the osteochondral lesion covered with autologous osteochondral transplantation ranged from 0.8 to 6 cm2 (average: 2.13 cm2). The diameter of the grafts used ranged from 6 to 10 mm and 1 to 6 grafts were used in each case to achieve >90% covering of the lesion area.
Conclusions: Both techniques offer satisfactory functional outcome and do not compromise the patients’ future options.

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