antibiotics | Acta Medica Marisiensis

Incidence of pathogens infections in a Romanian Intensive Care Unit and sensitivity to antibiotics. A prospective single center study

Bedreag Ovidiu Horea^1,2, Rogobete Alexandru Florin^1,2*, Luca Loredana¹, Neamtu Claudiu¹, Dragulescu Dorian Mihai¹, Nartita Radu^1,3, Papurica Marius^1,2

1 Clinic of Anesthesia and Intensive Care, Emergency County Hospital ”Pius Brinzeu”, Timisoara, Romania
2 Faculty of Medicine, ”Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
3 Faculty of Chemistry, Biology, Geography, West University of Timisoara, Timisoara, Romania

DOI: 10.1515/amma-2016-0001

Introduction: Nosocomial infections represent one of the biggest challenges faced by clinicians in the intensive care unit (ICU) and is associated with high morbidity and mortality. Infections in ICU are most often very serious and represent often the cause of hospitalization in intensive care clinics.
Aim of the study: This paper presents the incidence of nosocomial infections, and the sensitivity to antibiotics encountered in our ICU.
Material and Methods: This prospective study was conducted for two years at the Clinic of Anesthesia and Intensive Care, Emergency County Hospital “Pius Brinzeu” Timisoara, Romania. All patients admitted to the ICU were analyzed in terms of signs and symptoms of bacterial infections.
Results: A total of 1081 microbiological reports were recorded. Among these, 635 (58.70 %) represented infections in the respiratory tract, 201 (18.60 %) in the bloodstream, 100 (9.30 %) in genitourinary tract, and 10 (0.90 %) in the central nervous system. The top five most frequently identified pathogen in microbiological reports are Klebsiella sp (17.60 %), Acinetobacter sp (14.20 %), Proteus mirabilis (13.80 %), Pseudomonas aeruginosa (12.90 %), Staphylococcus aureus – MSSA (12.80%).
Conclusions: In order to choose empirical treatment, international guidelines should be consulted according to each pathology and adapted to the sensitivity encountered in the microbiology reports of the Critical Care Unit.

Objective: The purpose of this study was to analyze the quality of raw milk coming from two different livestock systems: semi-intensive farming and extensive farming.
Materials and methods: In this paper the milk was analyzed from the perspective of its most important quality indicators: the total number of germ, the somatic cell count and the presence of inhibitors. The study was conducted on 18 month period, between January 2011 and June 2012. The samples came from 6 semi-intensive farm system and from 6 collecting centers.
Results: Regarding the sanitary conditions and milk quality, over all, a significant difference between the two systems has been noted (p<0.001). The analysis of the samples that came from the semi-intensive farm system showed a high level of fit milk of up to 90%. So, this system is adequate for obtaining milk that corresponds with the directives imposed by the European Union to be obtained until December 2013.
Conclusions: Early detection of antibiotics and residues in raw milk may prevent the occurrence of risks to human health and may prevent significant economic loss for the milk processors.