Tag Archives: Borrelia burgdorferi

Lyme Meningoradiculitis: Case Reports and Literature Review

Smaranda Maier1,2, Nicoleta Stirbu1,2*, Zoltan Bajko1,2, Anca Moţăţăianu1,2, Brânduşa Ţilea1,2, Adrian Alexandrescu1,2, Rodica Bălaşa1,2

1 University of Medicine and Pharmacy Tirgu Mures, Romania
2 Mures County Clinical Emergency Hospital, Romania

DOI: 10.1515/amma-2016-0033

The clinical manifestations of Lyme disease are protean. The meningoradiculitis is a common and well-recognized complication of neuroborreliosis but can be easily misdiagnosed without a high degree of clinical suspicion, mainly if the tick bite is not present in the medical history. We report two cases of Lyme meningoradiculitis with excellent outcome after appropriate antibiotic therapy. In an endemic area in case of neurological manifestations suggestive for neuroborreliosis the serological testing for B. burgdorferi in serum and cerebrospinal fluid is imperative for the correct diagnosis.

Keywords: , ,
Full text: PDF

Relapsing Polychondritis Possibly Caused by Chronic Infection with Borrelia Burgdorferi: Case Report

Morariu SH1, Badea MA1, Cotoi OS2, Vartolomei MD3, Badea Iudita-Maria4, Suciu M5, Buicu F6

1 University of Medicine and Pharmacy of Tirgu-Mures, Romania
2 University of Medicine and Pharmacy of Tirgu-Mures, Romania, Department of Pathophysiology
3 University of Medicine and Pharmacy of Tirgu-Mures, Romania, Department of Molecular and Cell Biology
4 Clinic of Anesthesiology and Intensive Care Medicine, Emergency County Hospital of Tîrgu Mureș, Romania
5 University of Medicine and Pharmacy of Tirgu-Mures, Romania, Department of Prosthetic Dentistry and Oral Rehabilitation
6 University of Medicine and Pharmacy of Tirgu-Mures, Romania, Department of Public Health and Medicines Management

DOI: 10.1515/amma-2015-0018

Introduction: Relapsing polychondritis has been described by Rudolph von Jaksch Warthenhorst in 1923 under the name of polichondropathy. Although the etiology is unknown, an autoimmune mechanism is likely due to formation of autoantibodies to type II collagen in the extracellular matrix of the cartilage with its consequent destruction.
Case report: We present a case with relapsing polychondritis according to McAdam and Damiani criteria and with positive Western blot reaction for Ac IgG anti Borrelia burgdorferi. Serological reaction became negative and the patient presented favorable evolution at 6 months follow-up after corticosteroid therapy and antibiotics.
Conclusion: Chronic infection with Borrelia burgdorferi may play a role in relapsing polychondritis determinism

Keywords: ,
Full text: PDF