Tag Archives: antibiotic prophylaxis

Prescription of antibiotics in bone augmentation with dental implant

DOI: 10.2478/amma-2025-0014

Aim: To evaluate the success and failure in bone augmentation with dental implant cases when antibiotics were used with different timing in long follow-up periods.
Material and Method: 120 patients were randomly put into three groups: (1) no antibiotic treatment (NOAB); (2) preoperative and postoperative antibiotic treatment (PPAB) with 1.5 g of amoxicillin an hour before surgery and 500 mg three times a day for five days after surgery; and (3) postoperative antibiotic coverage (POAB) with 500 mg three times a day starting after surgery and continuing for five days after surgery. We conducted a comparison and follow-up of patients to detect antibiotic responses in the context of bone augmentation and dental implants.
Results: We recorded highly significant differences in age groups and gender. We observed highly significant differences (0.000, 0.000, and 0.041) on the third day, the 12th week, and after six months of follow-up. The results indicated that in group 1, 7 implants (11.6%) failed, while in group 3, only 2 implants (3.33%) failed. In contrast, in group two, all implants succeeded (100%).
Conclusion: The use of preventive antibiotics resulted in a very low infection rate. Conversely, the absence of preventive antibiotics significantly increased the infection rate. A higher number of studies were required to analyze the biological factors that contributed to failure in the case of various antibiotic doses and types.

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The Role of Antibiotic Prophylaxis in the Ureteroscopy Treatment for Ureteral Lithiasis

DOI: 10.2478/amma-2014-0025

Introduction: One of the most common pathologies in urological praxis is urinary lithiasis. Extracorporeal shock wave lithotripsy (ESWL) or frequently retrograde ureteroscopy are modern pathways in the treatment of this kind of pathology. There are certain problems which may develop after the ureteroscopy such as infection with fever complication.
Material and method: This retrospective study evaluates 164 patients who underwent ureteroscopy treatment over a period of two years (2011–2012). We compared the infection complication episode (with fever) in 33 (20.12%) patients with antibiotic prophylaxis (group A) versus 131 (79.87%) patients without prophylaxis (group B). Antibiotics used for prophylaxis were: amoxicilinum and clavulanic acid, generation I and II cephalosporines.
Results: Twenty-four (14.63%) patients presented postsurgical fever. Most febrile patients were those with grade II hydronephrosis – 16 (66.66%), of which 2 (6.06%) patients from group A and 14 (10.68%) from group B. From group A, 3 (12%) patients with stones below 10 mm had fever, while 18 (14.87%) from group B developed this complication. Among the patients with stones’ size over 10 mm, 1 (14.28) patient from group A and 2 (25%) patients from group B had fever.
Conclusions: Patients undergoing the ureteroscopy treatment should be investigated before the procedures for the presence of bacteria in order to avoid complications like infection associated with fever. Antibiotic prophylaxis may reduce the incidence of postoperative infection in the ureteroscopy treatment.

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