Tag Archives: body mass index

Packed cell volume and its relation to obesity, gender and smoking status

Bushra Khairuddin Abdulqader

Department of Medical Physiology, College of Medicine, University of Mosul, Mosul, Iraq

DOI: 10.2478/amma-2023-0047

Objective: Our aim was to evaluate the packed cell volume (PCV) correlation with body mass index, body fat percentage, also differences between genders and smokers & non-smokers, among Iraqi students.
Methods: A cross-sectional study was done on 112 healthy individuals (from which 52.7% were males), aged between 18-23 years old, in December 2022. A short informative history was taken through a questionnaire, anthropometric measures were taken to calculate body mass index and body fat percentage, and the determination of packed cell volume was done by the Microhematocrit method.
Results: Packed cell volume among males was higher 47.45±3.409% than for females 39.90±3.169%, with a difference statistically significant (p=0.000), also the correlation of PCV revealed direct significance with body mass index (p=0.011) and indirect statistically significant with body fat percentage (p=0.000). The prevalence rate of smoking was 13.4% and the level of PCV among smokers was 46.80±6.085%, significantly higher (p=0.015) than among non-smokers 43.43±4.702%.
Conclusion: Packed cell volume showed a direct correlation with body mass index, an inverse one with the body fat percentage, and was significantly higher among young smokers, emphasising the idea that this parameter can help to evaluate the health risk and to be included in preventive programs and assessment protocols.

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The impact of body mass index on lipid profile, blood pressure, and glycemic control in patients with type 2 diabetes mellitus: a comparative study

Alina Elena Răuță1, Robert Aurelian Tiucă2, Alina Dia Trâmbițaș-Miron3, Mariana Cornelia Tilinca4

1. UPU-SMURD, Emergency County Hospital, Târgu Mureș, Romania
2. Clinic of Endocrinology, Mureș County Clinical Hospital , Târgu Mureș, Romania
3. Department of Medical Informatics and Biostatistics, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania
4. Department of Internal Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania

DOI: 10.2478/amma-2021-0001

Objective: The aim of this study was to highlight the impact of body mass index on the lipid profile, blood pressure, and glycemic control in patients with type 2 diabetes mellitus.
Methods: We conducted an observational, retrospective study on 294 subjects with type 2 diabetes mellitus, hospitalized between 01.06.2018 – 01.06.2019. Subjects were divided into three groups according to body mass index value: group 1 – normal weight, group 2 – overweight, and group 3 – obesity.
Results: Out of the 294 subjects, 59.2% were females. There were 41 subjects in group 1, 89 subjects in group 2, and 164 subjects in group 3. The lipid profile was normal in 68.3% of cases in group 1, being abnormal in 49.4% of cases in group 2 and 56.1% of cases in group 3. We found a statistically significant difference between triglycerides levels in the three groups among males (P = <0.001) and females (P = 0.004). Arterial hypertension was found in 91.2% of cases, its prevalence being statistically significant higher in females (94.8%) than in males (85.8%) (P = 0.011). Most subjects had a poor glycemic control (89.1%) without any statistically significant differences among the three groups.
Conclusions: An increased body mass index in type 2 diabetes mellitus increases the prevalence of various cardiovascular risk factors such as arterial hypertension and dyslipidemia, while glycemic control seems more influenced by the duration of the disease.

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Body Mass Index and the Relationship with Chronic Kidney Disease in a Tertiary Care Hospital in Romania

Carmen Denise Caldararu1, Dorin Tarta1*, Raluca Pop2, Mirela Gliga1, Emilian Carasca3, Grigore Dogaru1

1 Department of Nephrology, University of Medicine and Pharmacy Targu Mures, Romania
2 Research Methodology Department, University of Medicine and Pharmacy Targu Mures, Romania
3 Department of Internal Medicine, University of Medicine and Pharmacy Targu Mures, Romania

DOI: 10.1515/amma-2016-0016

Obesity and chronic kidney disease are epidemic size. Chronic kidney disease (CKD) appears to be more common in obese, although interrelation is not supported by all authors. Aim: The aim of the study was to investigate the effects of overweight and obesity on glomerular filtration rate (GFR) and the relationship between body mass index (BMI) and other risk factors for CKD.
Methods: This is a cross-sectional study on 627 patients admitted in a Nephrology Department between January 2007 – December 2011. Patients were divided according to eGFR in a CKD group and a non-CKD group. Patients were divided based on BMI in: normal (<25 kg/m2), overweight (≥ 25 kg/m2 and ≤30 kg/m2) and obese (>30 kg/m2). Demographical, clinical and laboratory data (serum creatinine, lipid parameters, etc) were used for the statistical analysis. The relationship between BMI (as a marker of obesity and overweight), glomerular filtration rate and other possible risk factors for chronic kidney disease was studied.
Results: 43.70% patients were obese and 33.17% overweight. CKD prevalence was 58.69%. Logistic regression analysis showed that systolic blood pressure was the main determinant of CKD in our patients.
Conclusion: Lack of association between BMI and CKD was demonstrated in our study.

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Association of Heart Failure with Preserved Ejection Fraction and Components of Metabolic Syndrome

Anda-Mihaela Cerghizan1, Simona Bățagă2, L. Cozlea1, I.D. Tarța3, B. Chibelean 4, Carmen Căldăraru5*, G. Dogaru3

1 3rd Internal Medicine Clinic, Faculty of Medicine, University of Medicine and Pharmacy, Tirgu-Mures, Romania
2 1st Gastroenterology Clinic, Faculty of Medicine, University of Medicine and Pharmacy, Tirgu Mures, Romania
3 Department of Nephrology, University of Medicine and Pharmacy, Tirgu-Mures, Romania
4 Department of Urology, University of Medicine and Pharmacy, Tirgu-Mures, Romania
5 Department of Physiology, University of Medicine and Pharmacy, Tirgu-Mures, Romania

DOI: 10.1515/amma-2015-0078

The aim of the current study was to find any possible associations between elements of metabolic syndrome and echocardiographic characteristics (grade of diastolic dysfunction) in normoponderal and overweight patients with heart failure with preserved ejection fraction. A retrospective observational analytical study was performed on 130 patients presenting heart failure with documented ejection fraction over 50%. They were divided into two groups based on their body mass index. The first group included 56 normal weight patients and the second group included 74 overweight patients. Elements of the metabolic syndrome analysed in the current study were arterial hypertension, high triglyceride levels, low HDL-cholesterol and diabetes. None of the components of metabolic syndrome alone had a role in the evolution of diastolic dysfunction in either group. Three or four elements present in obese patients were negatively associated with grade 2 diastolic dysfunction, high values of blood pressure (over 180/110 mmHg) were more often encountered in obese patients with first and second grade of diastolic dysfunction.

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