radiotherapy | Acta Medica Marisiensis

Intersphincteric Resection for Low Rectal Cancer – Case Report

Russu Cristian¹, Molnar Călin^1*, Copotoiu Sanda Maria², Sărăcuț Claudiu¹, Gherghinescu Mircea¹, Molnar Varlam Claudiu³, Copotoiu Constantin¹

1 Surgical Clinic 1 of the Emergency County Hospital and the University of Medicine and Pharmacy of Tîrgu Mureș, Romania
2 Anesthesia and Intensive Care Clinic 1 of the Emergency County Hospital and the University of Medicine and Pharmacy of Tîrgu Mureș, Romania
3 Obstetric-Gynecology Clinic, Clinical Emergency County Hospital Tirgu Mures, University of Medicine and Pharmacy Tirgu Mures, Romania

DOI: 10.1515/amma-2015-0118

Introduction: Surgical treatment for low rectal cancer represents a challenge: to perform a radical resection and to preserve the sphincter’s function. We report a case of intersphincteric resection in a combined multimodality treatment for low rectal cancer, with good oncologic and functional outcome.
Case presentation: We report a case of a 73 years old woman admitted in April 2014 in surgery, for low rectal cancer. The diagnostic was established by colonoscopy and malignancy confirmed by biopsy. Complete imaging was done using computed tomography and magnetic resonance to establish the exact stage of the disease. The interdisciplinary individualized treatment began with radiotherapy (total dose of 50 Gy, administered in 25 fractions) followed by surgery after eight weeks. We performed intersphincteric rectal resection by a modified Schiessel technique. There were no postoperative complications and the oncologic and functional results were very good at one year follow up.
Conclusions: Intersphincteric resection, in this selected case of low rectal cancer, represented an efficient surgical treatment, with good functional results and quality of life for the patient. A multidisciplinary team is an invaluable means of assessing and further managing the appropriate, tailored to the case, treatment in the aim of achieving best results.

Remarks on Odontogenesis in Children After Chemo-radiation Therapy

Bică Cristina¹, Chinceşan Mihaela², Păcurar Mariana¹, Molnár Enikő³, Stolnicu Simona⁴

1 Department of Pediatric Dentistry, University of Medicine and Pharmacy, Tîrgu Mureș, Romania
2 Department of Pediatric Haematology-Oncology, University of Medicine and Pharmacy, Tîrgu Mureș, Romania
3 Emergency County Hospital, Tîrgu Mureș, Romania
4 Department of Pathology, University of Medicine and Pharmacy, Tîrgu Mureș, Romania

Introduction: Leukemias are the most frequent forms of neoplasias in children. The oral complications that occur in time, after the specific treatment through chemotherapy or radiotherapy, are represented by the occurrence of multiple carious lesions, disorders of dental eruptions, the premature loss of the primary teeth, anomalies in the development of teeth.
Material and method: Through the clinical examination of the oral cavity and through radiological examination, with the help of the orthopantomogram, we revealed the disorders of dental development consecutive to the cytostatic therapy and radiotherapy in the acute lymphoblastic leukemia.
Results: The specific treatment through chemotherapy and radiotherapy overlapped with important stages of the physiological process of odontogenesis. We noted ageneses, microdontias, precocious eruptions and disorders of the eruption order.
Conclusions: The cytostatic medication and radiotherapy can be followed by anomalies in the development and eruption of the dental buds. The severity of these secondary effects varies according to the patient’s age at the moment of the start of the specific therapy, the stage of dental development, the type of cytostatic medication and the dose and frequency of treatment cycles.